basic FUNCTION
| plays an important role in establishing kidney precursor cells, and in regulating their differentiation into kidney tubular tissue |
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required to limit endoderm differentiation from mesendoderm |
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zinc finger transcription factor |
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playing important roles in embryonic heart and urogenital development |
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OSR1 and OSR2 function is required for maintenance of expression of signaling molecules critical for joint formation, including GDF5, WNT4 and WNT9B |
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OSR1 and OSR2 function redundantly to control synovial joint formation |
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STK39 and OSR1 may be critical factors in the regulation of depolarizing GABA-mediated processes in the developing brain |
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involved in SLC12A3 phosphorylation with SPAK kinases |
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STK39 and OSR1 regulate sodium-chloride co-transporters SLC12A3, and SLC12A1 in a nephron-specific manner |
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STK39 and OSR1 associate with membranes as peripheral proteins and exhibited distinct subcellular and region-specific expression profiles throughout the lens |