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FLASH GENE
Symbol ACAA1 contributors: - updated : 13-10-2006
HGNC name acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase)
HGNC id 82
DNA
TYPE functioning gene
STRUCTURE 14.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
N terminal thiolase domain
HOMOLOGY
Homologene
FAMILY thiolase-like superfamily
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,peroxisome
basic FUNCTION
  • acetyl-CoA acyltransferase,(peroxisomal matrix 3-oxoacyl-CoA thiolase), medium or long chain, catalyzing the fourth step of fatty acid beta-oxidation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism energetic , lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS