Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PROS1 | contributors: mct - updated : 22-12-2009 |
HGNC name | protein S (alpha) |
HGNC id | 9456 |
|
DNA |
TYPE | functioning gene |
STRUCTURE | 101.05 kb 15 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
regulatory sequence | Promoter |
Binding site hormone HRE | |
text structure | |
|
MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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|
EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
| |
|
conjugated | GlycoP |
mono polymer | homomer , monomer , polymer |
HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | regulatory |
SUBCELLULAR LOCALIZATION | extracellular |
intracellular | |
intracellular,cytoplasm,cytosolic,granule | |
text | secreted from platelets alpha granules |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | coagulation/hemostasis , inflammation |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule | metal binding, |
cell & other |
REGULATION |
inhibited by | binding to C4BP |
Other | vitamin K-dependent |
ASSOCIATED DISORDERS |
corresponding disease(s) | PROS1 |
related resource | Protein S Deficiency: A database of Mutations |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |