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FLASH GENE
Symbol MYCT1 contributors: - updated : 10-02-2006
HGNC name myc target 1
HGNC id 23172
DNA
TYPE functioning gene
STRUCTURE 24.00 kb     2 Exon(s)
MAPPING cloned Y linked N status provisional
Physical map
RAET1E 6q25 retinoic acid early transcript 1E ULBP2 6q25 UL16 binding protein 2 ULBP1 6q25 UL16 binding protein 1 LOC345829 6q24.3 similar to Transcription factor BTF3 (RNA polymerase B transcription factor 3) LOC391980 6 similar to UL16 binding protein 1; alcan-beta RAET1L 6q25 retinoic acid early transcript 1L PHBP1 6q25 prohibitin pseudogene 1 ULBP3 6q25 UL16 binding protein 3 PPP1R14C 6q24.3-q25.3 protein phosphatase 1, regulatory (inhibitor) subunit 14C RNU4P1 6q25.1 RNA, U4 small nuclear pseudogene 1 (U4/7) LOC389434 6 similar to iodotyrosine dehalogenase protein PLEKHG1 6q25.1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 FTHFSDC1 6q25.1 formyltetrahydrofolate synthetase domain containing 1 LOC391982 6 similar to ribosomal protein S12 AKAP12 6q24-q25 a kinase (PRKA) anchor protein (gravin) 12 ZBTB2 6q25.1 zinc finger and BTB domain containing 2 C6orf96 6q25.1 chromosome 6 open reading frame 96 C6orf211 6q25.1 chromosome 6 open reading frame 211 C6orf97 6q25.1 chromosome 6 open reading frame 97 ESR1 6q25.1 estrogen receptor 1 SYNE1 6q25 spectrin repeat containing, nuclear envelope 1 MYCT1 6q25.1 myc target 1 VIP 6q24-q27 vasoactive intestinal peptide LOC391983 6 similar to Tubulin beta-2 chain FBXO5 6q25-q26 F-box only protein 5 MTRF1L 6q25-q26 mitochondrial translational release factor 1-like RGS17 6q25-q26 regulator of G-protein signalling 17 LOC389435 6 similar to 60S ribosomal protein L27a OPRM1 6q24-q25 opioid receptor, mu 1 PIP3-E 6q25.2 phosphoinositide-binding protein PIP3-E MAGI1 6q25.2 membrane associated guanylate kinase interacting protein-like 1 LOC391984 6 similar to stathmin-like 2; superiorcervical ganglia, neural specific 10 RBM16 6q25.1-q25.3 RNA binding motif protein 16 LOC389436 6 LOC389436 TFB1M 6q25.1-q25.3 transcription factor B1, mitochondrial NOX3 6q25.1-26 NADPH oxidase 3
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularvessel   highly
Lymphoid/Immunespleen    
cell lineage
cell lines laryngeal cancer
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Myct1
ortholog to ratrtus Myct1_predicted
Homologene
FAMILY
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • could promote apoptosis of gastric carcinoma (GC) cell lines
  • may play an important role in the carcinogenesis of GC
  • CELLULAR PROCESS cell cycle
    cell life, cell death/apoptosis
    nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in gastric cancer tissues
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS