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FLASH GENE
Symbol PEX11G contributors: npt/ - updated : 15-03-2006
HGNC name peroxisomal biogenesis factor 11 gamma
HGNC id 20208
DNA
TYPE functioning gene
STRUCTURE 12.15 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 1143 - 241 - -
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
 pancreas exocrine    
 stomach   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two putative transmembrane segments, showing 22p100 and 23p100 AAs identity to PEX11A and PEX11B (Tanaka 2003)
  • HOMOLOGY
    Homologene
    FAMILY
  • peroxin-11 family
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,peroxisome
    text peroxisomal membrane protein
    basic FUNCTION
  • may play a role in peroxisome homeostasis such as regulation of organelle abundance
  • may alos be involved in peroxisome proliferation
  • phosphorylation-dependent activation of peroxisome proliferator protein PEX11G controls peroxisome abundance (Knoblach 2010)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS