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FLASH GENE
Symbol H2AC1 contributors: mct - updated : 15-10-2021
HGNC name H2A clustered histone 1
HGNC id 18729
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text component of the HIST1 cluster on chr 6p
STRUCTURE 0.50 kb     1 Exon(s)
text structure
  • intronless gene
  • histone H3 K9 acetylation levels in the promoter regions of both H2AFZ and H2AW were clearly higher than that in the promoter region of H2AC1
  • MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    text transcripts contain a palindromic termination element
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 500 14.1 131 - 2016 26649967
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
  • histone H2A family
  • CATEGORY structural protein , DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome,nucleosome
    intracellular,nucleus,chromatin/chromosome,telomere
    basic FUNCTION
  • nucleosome assembly activity
  • H2AC1, H2BC1 and NPM2 enhance reprogramming of human somatic cells and improve the quality of human induced pluripotent stem cells (iPSCs)
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
  • HIV-1 Tat peptides binding
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS