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FLASH GENE
Symbol INSM2 contributors: mct - updated : 08-01-2014
HGNC name insulinoma-associated 2
HGNC id 17539
DNA
TYPE functioning gene
STRUCTURE 3.01 kb     1 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 3024 - 566 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
five C2H2-type zinc fingers
HOMOLOGY
interspecies homolog to murine Insm2
Homologene
FAMILY
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
intracellular,nucleus
basic FUNCTION may be associated with the transformation of neuroendocrine cells
CELLULAR PROCESS nucleotide, transcription
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA binding
RNA
small molecule metal binding,
Zn2+
protein
  • INSM2 plays potentially an important role in the differentiation cascade of NEUROG3/NEUROD1 signaling in pancreatic islets
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS