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FLASH GENE

Symbol

LSM6

contributors: - updated : 30-05-2005

HGNC name	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
HGNC id	17017

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	14.00 kb     4 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart         Lymphoid/Immune lymph node         Nervous

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

SM sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop

HOMOLOGY

interspecies

ortholog to rattus LOC498934

Homologene

FAMILY

snRNP SM proteins family

CATEGORY

RNA associated

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION	may play a role in U4/U6 snRNP formation
	may form a stable heteromer present in tri-snRNP particles which are important for pre-mRNA binding

CELLULAR PROCESS

nucleotide, RNA splicing

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA	binding to the U6 snRNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS