Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol DPP7 contributors: - updated : 17-03-2004
HGNC name dipeptidylpeptidase 7
HGNC id 14892
DNA
TYPE functioning gene
STRUCTURE 4.00 kb     13 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
peptidase S28 motif
secondary structure N-glycosylated protein
mono polymer homomer , dimer
HOMOLOGY
interspecies ortholog to rattus Dpp7
intraspecies homolog to PCP
Homologene
FAMILY DASH protein
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,lysosome
intracellular,cytoplasm,cytosolic,vesicle
basic FUNCTION
  • prolylcarboxypeptidase activity
  • plays an important role in the degradation of collagen and some oligopeptides, releasing a N-terminal dipeptide
  • active at both acidic and neutral pH
  • CELLULAR PROCESS protein, post translation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    inhibited by Lys-thiazolidide and Lys-piperidide
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS