Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | SLC30A5 | contributors: mct - updated : 06-02-2018 |
HGNC name | solute carrier family 30 (zinc transporter), member 5 |
HGNC id | 19089 |
|
DNA |
TYPE | functioning gene |
STRUCTURE | 37.12 kb 18 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
| moderately in blood and lymph | |
at STAGE |
physiological period | fetal, pregnancy |
Text | pancreas, placenta |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
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HOMOLOGY |
interspecies | homolog to rattus Slc30a5 (94.9 pc) |
homolog to murine Slc30a5 (95.4 pc) |
Homologene |
FAMILY |
CATEGORY | transport carrier |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,Golgi | |
intracellular,cytoplasm,organelle,endosome | |
intracellular,cytoplasm,cytosolic,vesicle | |
intracellular,nucleus,nucleolus | |
text | |
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basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | facilitated diffusion transport |
text | |
| |
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PATHWAY |
metabolism | metal |
signaling |
a component | heterodimerizing with SLC30A6 (cytosolic C-terminal tail of SLC30A5 is important in determining SLC30A6 as a partner molecule for heterodimer formation) |
INTERACTION |
DNA |
RNA |
small molecule | metal binding, |
protein |
cell & other |
REGULATION |
Other | zinc-mediated transcriptional repression of the human SLC30A5 gene involves the zinc-dependent binding of a zinc-regulated protein factor to a palindromic sequence, the ZTRE, upstream of the end of the 5& | |
8242;-UTR |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |