basic FUNCTION
| promoting the priming of synaptic vesicles by acting through syntaxin |
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mediated vesicle priming not restricted to neurotransmitter release but is also functional in insulin secretion |
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playing a potential role in mediating some of the acute and chronic changes in MC produced by exposure to hyperglycemia |
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with DOC2B are implicated in Ca2+-dependent neurotransmitter release |
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RAB3IL1 and its binding partner UNC13B, and the subsequent gating of vesicle fusion by activation of the Ca2+ channels, are implicated in the docking of vesicles at the transmitter release site, a process of neurosecretion |
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having essential function in synaptic vesicle priming and in the modulation of synaptic strength, and key regulator of these adaptive mechanisms |
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essential regulator of synaptic vesicle priming and playing a key role in adaptive synaptic plasticity phenomena |
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RAB34 and its effector UNC13B constitute a new pathway modulating protein secretion in the cellular response to hyperglycemia |
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UNC13B and UNC13C limit the ability of UNC13A to regulate calcium-dependent replenishment of readily releasable pool and slow pool to fast pool conversion in central synapses |