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FLASH GENE
Symbol DCAF11 contributors: npt/ - updated : 05-12-2003
HGNC name DDB1 and CUL4 associated factor 11
HGNC id 20258
DNA
TYPE functioning gene
STRUCTURE 10.43 kb     15 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
15 - 4311 61.7 546 - Choe (2009)
15 - 3663 58.8 520 - Choe (2009)
lacking an in frame segment in the coding region
- - 3861 - 546 - Choe (2009)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Nervousbrain    
Respiratorylung    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven WD repeats
  • HOMOLOGY
    interspecies homolog to murine Wdr23
    Homologene
    FAMILY
  • WD repeat family
  • CATEGORY regulatory , structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • regulates SKN-1 target genes downstream from p38 mitogen-activated protein kinase, glycogen synthase kinase 3, and insulin-like receptor pathways (Choe 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS