Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ART4 contributors: - updated : 10-11-2006
HGNC name ADP-ribosyltransferase 4 (Dombrock blood group)
HGNC id 726
DNA
TYPE functioning gene
STRUCTURE 14.00 kb     3 Exon(s)    1 Copie(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text two alternate isoforms
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
 vessel   highly
Lymphoid/Immunespleen   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticmonocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
interspecies ortholog to murine Art4
ortholog to chimpanzee art4
Homologene
FAMILY Arg-specific ADP-ribosyltransferase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     plasma membrane
text attached to the membrane by a GPI-anchor
basic FUNCTION
  • acting as blood group antigen
  • involved in the transfer of the ADP-ribose moiety from NAD+ to a specific amino acid in the target protein
  • CELLULAR PROCESS protein, post translation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor, nucleotide,
    NAD+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) DO
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS