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FLASH GENE
Symbol EIF3K contributors: KTN/npt - updated : 17-08-2007
HGNC name eukaryotic translation initiation factor 3, subunit K
HGNC id 24656
DNA
TYPE functioning gene
STRUCTURE 17.00 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 910 25.1 218 - -
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Endocrineparathyroid   highly
Reproductivefemale systemovary  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow  highly
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • EIF3S11 family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     plasma membrane,junction,adherens
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • tethering microtubule plus ends to the actin-rich cellular cortex
  • involved in the translation initiation
  • CELLULAR PROCESS protein
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • of the eukaryotic transcription initiation factor 3 multisubunit complex
  • of a multiprotein complex at adherens junction
  • INTERACTION
    DNA
    RNA binding to the 40S ribosome and promoting the binding of MET tRNA and mRNA
    small molecule
    protein
  • binding directly to dynein intermediate chain DNCI1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS