basic FUNCTION
| involved in the activation of a meiotic genes activation pathway |
|
promotes mitotic entry and maintenance in human cells by inhibiting protein phosphatase 2A (PP2A) |
|
crucial for mediating this regulation in somatic human cells |
|
mediates mitotic entry and maintains the mitotic state by inhibiting PP2A, and thus maintains the correct equilibrium between cyclin B-Cdc2 and PP2A |
|
essential kinase for correct chromosome condensation and mitotic progression |
|
enhances cyclin B1-Cdk1-dependent mitotic phosphorylation events, directing mitotic entry, anaphase and cytokinesis |
|
phosphorylating in mitosis ENSA, converting ENSA into a potent and specific inhibitor of PPP2R2B/PPP2R2D |
|
is required to maintain mitosis through PPP2R2B inhibition |