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FLASH GENE
Symbol PIR contributors: - updated : 03-12-2005
HGNC name pirin (iron-binding nuclear protein)
HGNC id 30048
DNA
TYPE functioning gene
STRUCTURE 108.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 1292 32.1 290 - Wendler
encoding the same protein than variant 2
- splicing 1318 32.1 290 - Wendler
encoding the same protein than variant 1
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveliver   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY pirin family, cupin superfamily
CATEGORY regulatory , transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
text predominantly localized in dot-like subnuclear structures
basic FUNCTION
  • being a putative cofactor of the NFI/CTF1 transcriptional activator
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    text putative cofactor of the NFI/CTF1 transcriptional activator
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binding to NF1/CTF1 and BCL3
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS