basic FUNCTION
| involved in transcriptional regulation |
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critical regulator involved in apoptosis and cell survival for immune-related cells |
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is an essential transcriptional regulator for hematopoietic differentiation in blood islands |
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involved in apoptosis, development and primitive hematopoiesis |
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is a critical regulator in peripheral T cell homeostasis and its TCR-mediated response |
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plays crucial roles as a novel cell-intrinsic factor both in peripheral T cell homeostasis and in TCR-mediated cellular response |
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roles of ZFAT in haematopoietic and angiogenesis, and possible involvement of ZFAT in haematopoietic malignancies |
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critically participates in the development of double-positive (DP) thymocytes through regulating the activities of MAPK14 and JNK |
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transcriptional regulator, involved in autoimmune thyroid disease, apoptosis, and immune-related cell survival |
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regulates the transcription of target genes by binding directly to the transcription start site (TSS) proximal region, and ZFAT-target genes play important roles in T-cell homeostasis |