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FLASH GENE
Symbol POTED contributors: mct/npt - updated : 14-03-2014
HGNC name POTE ankyrin domain family, member D
HGNC id 23822
DNA
TYPE functioning gene
STRUCTURE 32.41 kb     11 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
11 - 1826 66.4 584 - 2006 1639721
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemovary   
 female systemplacenta   
 male systemtestis  predominantly Homo sapiens
 male systemprostate   
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductivespermatid Homo sapiens
Reproductivespermatocyte
cell lineage
cell lines prostatic cancer cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N-terminal cysteine rich domain (CRD), palmitoylated on paired cysteine residues in each CRD motif (palmitoylation is responsible of the strong association with plasma membrane)
  • seven ankyrin repeats
  • spectrin-like helices
  • an alpha-helical C terminus
  • HOMOLOGY
    intraspecies paralog to POTEB, POTEG, POTEH, POTEA, POTEF, POTEE, POTEK
    Homologene
    FAMILY
  • POTE gene family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • playing an important role in reproductive processes
  • might be involved in transmitting signals from the cell surface (Bera 2004)
  • may have a role in apoptosis in the human testis, and involved in apoptosis of testicular germ cells
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • may have a role in apoptosis in the human testis
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS