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FLASH GENE
Symbol ABCC13 contributors: - updated : 22-12-2004
HGNC name ATP-binding cassette, sub-family C (CFTR/MRP), member 13
HGNC id 16022
DNA
TYPE functioning gene
STRUCTURE 70.00 kb     14 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 4166 - 140 - Allikmets
- splicing 2861 - 274 - Allikmets
6 exons
- splicing 826 - 169 - Allikmets
- splicing 1073 - 245 - Allikmets
- - 3389 - 325 - Yabuuchi
18 exons
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainforebraincerebral cortex  
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
Nervouscentral   
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
Blood/Hematopoieticmonocyte
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text fetal tissues,liver bone marrow and colon
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two transmembrane domains
  • a C-terminal NBF domains
  • three motifs Walker A and Walker B
  • HOMOLOGY
    intraspecies homolog to ABCC2
    Homologene
    FAMILY ABC transporter, MRP subfamily
    CATEGORY transport
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • participating directly in the active transport of drugs into subcellular organelles or influencing drug distribution indirectly
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS