basic FUNCTION
| palmitoyl acyltransferase |
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stimulates palmitoylation of tetraspanins CD9 and CD151 |
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ZDHHC2-dependent palmitoylation had multiple functional effects, promoting physical associations between CD9 and CD151, and between alpha3 integrin and other proteins |
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important role for DHHC2-mediated palmitoylation of CKAP4 in opposing cancer-related cellular behaviors, supporting the idea that DHHC2 is a tumor suppressor |
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with ZDHHC3, are differentially regulated and dynamic recruitment of protein palmitoylation machinery enables compartmentalized regulation of protein trafficking in response to extracellular signals |
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candidate enzyme to regulate SNAP25/23 palmitoylation dynamics at the plasma membrane |
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mediates de novo and turnover palmitoylation of R7BP ( |
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localizes to dendritic vesicles of unknown origin in neurons, where it regulates dynamic palmitoylation of DLG4 |
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capable of palmitoylating of Lck in T cells ( |
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DHHC17, DHHC18, ZDHHC2, exhibited weak or moderate activities |