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FLASH GENE
Symbol NUDT13 contributors: mct - updated : 02-06-2022
HGNC name nudix hydrolase 13
HGNC id 18827
DNA
TYPE functioning gene
STRUCTURE 21.37 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
10 - 2173 - 226 - 2006 16385451
9 - 2066 - 155 - 2006 16385451
9 - 2101 - 352 - 2006 16385451
8 - 1994 - 155 - 2006 16385451
8 - 1989 - 235 - 2006 16385451
7 - 1834 - 263 - 2006 16385451
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
cell lineage
cell lines
fluid/secretion blood
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • mutT domain
  • a sequence motif characteristic of the NADH pyrophosphohydrolase subfamily of Nudix hydrolases
  • HOMOLOGY
    interspecies homolog to murine Nudt13
    Homologene
    FAMILY NUDIX family of hydrolases
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    basic FUNCTION
  • nucleoside triphosphate pyrophosphohydrolase activity
  • may act to regulate the concentration of mitochondrial reduced pyridine nucleotide cofactors and the NAD(P)+/NAD(P)H ratio in mitochondria
  • potentiial role in the regulation of NAD(P)H pools
  • both the uncharacterized MFSD4A and NUDT13 may have a role in the regulation of the epithelial-mesenchymal transition (EMT)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS