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FLASH GENE
Symbol NUDT12 contributors: - updated : 13-11-2006
HGNC name nudix (nucleoside diphosphate linked moiety X)-type motif 12
HGNC id 18826
DNA
TYPE functioning gene
STRUCTURE 13.00 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Skin/Tegumentskin    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an ankyrin repeat in its N-terminal half
  • a consensus Nudix (Nudt) motif
  • an NADH diphosphatase-like sequence in its C-terminal half
  • HOMOLOGY
    interspecies homolog to murine Nudt12
    Homologene
    FAMILY
  • NUDIX family of hydrolases
  • NudC subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,peroxisome
    basic FUNCTION
  • having hydrolase activity
  • may act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
  • magnesium
  • manganese
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS