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FLASH GENE
Symbol KRTAP4-2 contributors: npt/ - updated : 11-06-2009
HGNC name keratin associated protein 4-2
HGNC id 18900
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text KAPs cluster
STRUCTURE 0.76 kb     1 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 782 14.3 136 - Rogers (2001)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Skin/Tegumentskin appendageshair   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • highly conserved amino-terminal end region, MV(S/N)SCC
  • a central region of highly repetitive
  • di-cysteine-containing pentamers, separated by occasional pentameric, non-repetitive segments
  • HOMOLOGY
    Homologene
    FAMILY
  • ultrahigh sulfur KAP family
  • KRTAP type 4 family
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,intermed filament
    basic FUNCTION
  • involved in formation of the matrix associated with keratin intermediate microfilaments
  • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    text hair fibers formation
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS