basic FUNCTION
| RNA methyltransferase involved in the first step in processsing of preribosomal RNA |
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function as E3 ligases based on its capacity for self-ubiquitination (Takeyama 2003) |
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involved in the assembly and metabolism of SnoRNPs in the SMN complex |
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has an important role in pre-rRNA processing during ribosomal biogenesis |
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would play a critical role in the maintenance of nuclear shape and cellular growth |
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WWE-RING-finger protein and involved in regulating heart development and heart functions |
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can act as a negative regulator of Notch signals in T cells but that endogenous levels of DTX1 and DTX2 are not important for regulating Notch signals during thymocyte development |