Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ERGIC2 contributors: mct/npt - updated : 30-06-2010
HGNC name ERGIC and golgi 2
HGNC id 30208
DNA
TYPE functioning gene
STRUCTURE 40.56 kb     14 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
14 - 1781 45 377 - Kwok (2006)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   highly
Endocrineparathyroid   highly
Lymphoid/Immunethymus    
Reproductivemale systemprostate  highly
Urinarykidney    
cell lineage
cell lines
fluid/secretion blood
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to yeast Erv41p
ortholog to murine 1200009B18Rik
homolog to zebrafish zgc64005
Homologene
FAMILY
  • ERGIC family
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,Golgi
    intracellular,nucleus
    text in the nuclei of glandular epithelia of prostate
    basic FUNCTION
  • playing an important role in the growth and tumorigenicity of PC-3 prostate tumor cells
  • involved in protein trafficking between ER and Golgi
  • involved in protein transportation, and participated in the elongation factor 1 alpha regulated mechanisms (Yang 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • ERGIC2-ERGIC3 complex involved in transport between the endoplasmic reticulum and Golgi complex
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in prostate carcinoma (see TSG12B)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS