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FLASH GENE
Symbol AADAT contributors: - updated : 22-09-2007
HGNC name aminoadipate aminotransferase
HGNC id 17929
DNA
TYPE functioning gene
STRUCTURE 30.00 kb     13 Exon(s)
10 Kb 5' upstream gene genomic sequence study
motif repetitive sequence
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text Variants 1 and 2 encode the same isoform
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2326 47 425 - Goh
- - 2108 47 425 - Goh
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
Endocrinepancreas   lowly
Hearing/Equilibriumearinnercochlea highly
Reproductivefemale systemuteruscervix lowly
 male systemtestis  highly
 male systemprostate  lowly
Urinarykidney   lowly
Visualeye   lowly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • mitochondrial leader cleavage signal
  • pyridoxal-phosphate binding site
  • HOMOLOGY
    interspecies ortholog to murine Aadat
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • involved in the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS