basic FUNCTION
| playing a role in clathrin-mediated endocytosis of synaptic vesicles |
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may act as an alternate adaptor in several endocytic pathways |
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involved in clathrin-mediated synaptic vesicle endocytosis (an additional mechanism for generation of uniformly sized synaptic vesicles) |
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EPN1 and huntingtin-interacting protein 1 (HIP1) are endocytic accessory proteins ( |
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EPN1 and HIP1 in the synapse: as broadly required factors for promoting clathrin assembly and as adaptors for specific endocytic pathways |
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participatong in clathrin-mediated synaptic vesicle endocytosis at a central synapse |
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promotes endocytosis of the ubiquitinated EGFR |
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endocytic adaptor with putative functions in general aspects of clathrin-mediated endocytosis as well as in the internalization of specific membrane proteins |
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role of epsin as a specialized endocytic adaptor, with a critical role in the activation of Notch signaling |
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endocytic adapter protein, regulating mitotic membrane morphology and spindle integrity |
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epsin-induced membrane curvature is required for proper spindle morphogenesis, independent of its function in endocytosis during interphase |
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adaptor protein complex-2 and EPN1 are both critical mediators of agonist-stimulated F2R internalization |