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FLASH GENE

Symbol

VPS41

contributors: npt/ - updated : 13-08-2007

HGNC name	vacuolar protein sorting 41 homolog (S. cerevisiae)
HGNC id	12713

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	185.26 kb     28 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 4894 98.5 854 - McVey variant 2 - initiation site 4819 90 779 - McVey downstream initiation site, same reading frame

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive liver         Nervous brain         Reproductive male system prostate       Respiratory lung         Urinary kidney

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a 7-fold repeat common to clathrin and VPS proteins (two repeats)
	an ATP/GTP site
	a RING zinc finger motif

HOMOLOGY

Homologene

FAMILY

VPS41 family

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic,vesicle
text	intracellular vesicles that originated from Golgi and shoned partial coincidence with the delta subunit of adaptor protein complex-3

basic FUNCTION

formation and fusion of transport vesicles from the Golgi

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

cellular trafficking transport

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	nucleotide,
	ATP

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS