Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol IPPK contributors: mct/npt - updated : 16-04-2010
HGNC name inositol 1,3,4,5,6-pentakisphosphate 2-kinase
HGNC id 14645
DNA
TYPE functioning gene
STRUCTURE 57.08 kb     13 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
13 - 4401 - 491 - Verbsky (2002)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Endocrineplacenta   highly
Nervousbrain   highly
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a nuclear import signal
  • a peptide segment mediating the nuclear export of IPPK (Brehm 2007)
  • HOMOLOGY
    interspecies homolog to murine Ippk (91.4pc)
    homolog to rattus Ippk (92.2pc)
    Homologene
    FAMILY
  • IPK1 type 2 family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus,chromatin/chromosome
    intracellular,nucleus,nucleolus
    text preferentially localized in euchromatin and nucleoli, and co-localized with mRNA (Brehm 2007)
    basic FUNCTION
  • catalyzing the synthesis of inositol hexakisphosphate
  • plays a previously uncharacterized role in ciliary function (Sarmah 2007)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism alcohol , carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP binding
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS