Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PRPF6 | contributors: mct - updated : 03-12-2020 |
HGNC name | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) |
HGNC id | 15860 |
|
DNA |
TYPE | functioning gene |
STRUCTURE | 52.02 kb 21 Exon(s) |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
---|
|
EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
cell lineage
cell lines
| fluid/secretion
| lymph | |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
HOMOLOGY |
interspecies | homolog to yeast S.pombe Prp1p/Zer1p |
homolog to yeast S.cerevisiae Prp6p | |
homolog to murine Prpf6 (98.3pc) | |
homolog to rattus Prpf6 (98.2pc) |
Homologene |
FAMILY |
CATEGORY | RNA associated , transport |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,nucleus |
basic FUNCTION | |
| |
| |
|
CELLULAR PROCESS | nucleotide, RNA splicing |
PHYSIOLOGICAL PROCESS | mitochondrial transport |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
| |
|
cell & other |
REGULATION |
Other | strucutural integrity of the N-terminus is required to mediate a splicing event, but is not necessary for the assembly of spliceosomes (Lützelberger 2010) |
ASSOCIATED DISORDERS |
corresponding disease(s) | RP60 |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |