Selected-GenAtlas references SOURCE GeneCards NCBI Gene Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ARL6IP2 contributors: mct/npt - updated : 10-07-2008
HGNC name ADP-ribosylation factor-like 6 interacting protein 2
HGNC id 24047
DNA
TYPE functioning gene
STRUCTURE 81.00 kb     13 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 2279 66.2 579 - Gorry (unpublished), Ingley (1999)
- splicing - 66.2 583 - Gorry (unpublished)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
 salivary gland   highly
Endocrinepancreas   moderately
Lymphoid/Immunethymus   highly
Nervousbrain   moderately
 spinal cord   highly
Reproductivemale systemprostate  moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscularstriatumskeletal  
Nervouscentral   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal domain
  • guanylate binding protein
  • ATP/GTP-binding site motif A (P-loop)
  • ring-type zinc finger
  • N- and C-termini facing the cytoplasm
  • conjugated HemoP
    HOMOLOGY
    interspecies ortholog to murine Arl6
    Homologene
    FAMILY
  • GBP family, atlastin family of GTPases
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    intracellular,cytoplasm,organelle,Golgi
    text localize prominently to ER membranes along microtubules
    basic FUNCTION
  • GTPase functioning prominently in both ER and Golgi morphogenesis, but they do not appear to be required generally for anterograde ER-to-Golgi trafficking
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP
  • GTP
  • protein
  • binding to ARL6
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS