protein
| MAP3K5 |
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CDC16, CDC27, hCRY2, HSP90-GR complex |
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mediates lipid metabolism through reciprocal control of glucocorticoid receptor and peroxisome proliferator-activated receptor-& |
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947; (PPARG) |
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is a novel target of S100 proteins ( |
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binding of S100A1, S100A2, S100A6 and S100B, which interact with the TPR domain of PPP5C, leading to a full activation of the enzyme ( |
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MAP3K5 similar to HSP90AA1, associates with PPP5C through its TPR domains, and thereby, PPP5C dephosphorylates the essential pThr-845 in the kinase domain of MAP3K5 ( |
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S100A1, S100A2, S100A6, and S100B proteins specifically interact with PPP5C-tetratricopeptide repeat (TPR) domain |
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modulates SMAD3 function in the TGFB pathway |
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KLHDC10 bound to the phosphatase domain of PPP5C and suppressed its phosphatase activity |
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caveolin-1 is a novel physiological activator of PPP5C |
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HSPA8 recruits PPP5C and activates its phosphatase activity which suggests dual roles for PPP5C that might link chaperone systems with signaling pathways in cancer and development |
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differential responsiveness of PPP5C-MAPK1 and PPP5C-MAPK2 interactions to select oncogenic RAS variants ( |