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FLASH GENE
Symbol PGRMC2 contributors: npt - updated : 24-05-2005
HGNC name progesterone receptor membrane component 2
HGNC id 16089
DNA
TYPE functioning gene
STRUCTURE 17.66 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 1873 23.8 223 - -
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta, preferentially
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a putative transmembrane domain
  • a highly conserved stretch of 58AA
  • HOMOLOGY
    interspecies homolog to murine Pgrmc2
    homolog to rattus 25Dx
    homolog to Drosophilia Cg9066
    intraspecies homolog to PGRMC1
    Homologene
    FAMILY
  • cytochrome b5 family
  • MAPR subfamily
  • CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • receptor for progesterone
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule other,
  • steroid (like progesterone)
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS