Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | GRIN3B | contributors: mct - updated : 07-10-2011 |
HGNC name | glutamate receptor, ionotropic, N-methyl-D-aspartate 3B |
HGNC id | 16768 |
|
DNA |
TYPE | functioning gene |
STRUCTURE | 9.29 kb 9 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | N | status | provisional |
regionally located | . located between WDR18 and C19orf6 (membralin) |
RNA |
TRANSCRIPTS | type | messenger |
---|
text | previously uncharacterized regulation of NMDA receptor function by alternative splicing of the GRIN3B subunit (PMID: 21320125) |
|
EXPRESSION |
Type | restricted |
tissue |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
physiological period | pregnancy |
Text | embryonic tissue |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
| |
| |
|
conjugated | GlycoP |
mono polymer | heteromer , trimer , complex |
isoforms | Precursor |
HOMOLOGY |
interspecies | homolog to murine Grin3b |
homolog to murine Nr3b |
intraspecies | homolog to GRIN3A |
Homologene |
FAMILY | |
|
CATEGORY | regulatory , receptor membrane , transport channel |
SUBCELLULAR LOCALIZATION | plasma membrane |
text | postsynaptic membrane |
basic FUNCTION | |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | development , nervous system |
text | |
|
PATHWAY |
metabolism |
signaling | neurotransmission |
a component | |
|
INTERACTION |
DNA |
RNA |
small molecule | metal binding, |
protein | |
| |
|
cell & other |
REGULATION |
Other | unaffected by glutamate and NMDA |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
|
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |