Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol EIF3B contributors: - updated : 17-08-2007
HGNC name eukaryotic translation initiation factor 3, subunit B
HGNC id 3280
DNA
TYPE functioning gene
STRUCTURE 25.00 kb     19 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 3009 - 814 - ElAntak
- - 3084 - 814 - ElAntak
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon highly
 mouth   highly
Respiratoryrespiratory tractlarynx  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a RNA recognition motif, RRM
HOMOLOGY
interspecies homolog to yeast S.cerevisiae Prt1
Homologene
FAMILY eukaryotic translation initiation factor family
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic,ribosome
basic FUNCTION
  • stabilizing initiator Met tRNA (TRIMs) binding to 40S subunits
  • promoting the association of Met-tRNA and mRNA
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component components of the EIF3 multiprotein complex, 600kDa
    INTERACTION
    DNA
    RNA binding to the 40S ribosome
    small molecule
    protein EIF3A
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS