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FLASH GENE
Symbol B3GNT3 contributors: - updated : 27-01-2005
HGNC name UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
HGNC id 13528
DNA
TYPE functioning gene
STRUCTURE 17.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
digestiveesophagus    
Digestiveintestinelarge intestinecolon  
 intestinesmall intestinejejunum  
 stomach    
Respiratoryrespiratory tracttrachea   
cells
SystemCellPubmedSpeciesStageRna symbol
Skin/Tegumentkeratinocyte
cell lineage
cell lines colon cancer cell line
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal cytoplasmic domain
  • a transmembrane segment
  • a stem region
  • a catalytic domain with three N glycosylation sites
  • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to murine B3gnt3
    Homologene
    FAMILY beta-1,3-N-acetylglucosaminyltransferase family
    CATEGORY enzyme , transport
    SUBCELLULAR LOCALIZATION     plasma membrane
    text
  • type II transmembrane protein
  • basic FUNCTION
  • biosynthesis of poly-N-acetyllactosamine chainsof the backbone structure of dimeric sialyl Lewis x
  • involved in L selectin biosynthesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text lymphocyte homing,lymphocyte trafficking
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS