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FLASH GENE
Symbol KCNK13 contributors: mct/npt - updated : 02-03-2009
HGNC name potassium channel, subfamily K, member 13
HGNC id 6275
DNA
TYPE functioning gene
STRUCTURE 124.00 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
2 - 2517 45.4 408 - Theilig (2008)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Urinarykidneytubulecollecting duct   Homo sapiens
 kidneytubuleconvoluted tubuleproximal tubule  Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
intraspecies homolog to KCNK12 (60 p100)
Homologene
FAMILY
  • KCNK family
  • two pore domain potassium channel family
  • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • may be involved in both the maintenance of neuronal phenotype and in the specific functional role of these neurons in their respective networks (Jezzini 2004)
  • KCNK12, KCNK13 form active heteromeric channels, further expanding the known repertoire of K(+) channels
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text potassium channel
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS