SUBCELLULAR LOCALIZATION
| plasma membrane
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| intracellular
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| intracellular,cytoplasm,organelle,mitochondria
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| intracellular,cytoplasm,organelle,membrane
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text
| co-localize with SLC9A3R1 in the apical membrane of principal cells of the epididymis and the vas deferens |
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present in plasma membrane and mitochondria of astrocytes and catecholaminergic neurons, suggesting that it plays a role in the energetic status of these cells |
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the display of AQP9 at the plasma membrane depends on AQP9 phosphorylation, which appeared to be regulated through a RAC1-dependent pathway |
basic FUNCTION
| aquaglyceroporins, that transport glycerol |
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and small solutes in addition to water (Sorani 2008) |
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rapid cellular uptake or exit of metabolites with minimal osmotic perturbation |
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mediates passage of a wide variety of non-charged solutes |
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including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner |
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major aquaglyceroporin of the epididymis, liver, and peripheral leukocytes |
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plays an active role in neutrophil volume regulation and migration |
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is the primary route of hepatocyte glycerol uptake for gluconeogenesis |
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plays an important role in the development of microgravity-induced bone loss |
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facilitates diffusion of water and energy substrates such as glycerol and monocarboxylates ' |
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urea channel, involved in hepatocyte urea release, and constituting primary but redundant urea facilitator in hepatocytes, potentially |
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facilitates both single cell and multi-cellular migration, and increases the cellular density in the monolayer |