Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol IMMP2L contributors: mct - updated : 06-09-2011
HGNC name IMP2 inner mitochondrial membrane protease-like (S. cerevisiae)
HGNC id 14598
DNA
TYPE functioning gene
STRUCTURE 899.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map cen - D7S2504 - D7S2425 - D7S2456 - NRCAM - D7S692 - IMMP2L - D7S623 - D7S522 - qter
Authors Petek (01)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue  moderately
Reproductivefemale systemplacenta  moderately
Urinarykidney   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
cell lineage
cell lines
fluid/secretion blood
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an N terminal transmembrane domain
  • a signal peptidase 1 domain (anchored in the cytoplasmic membrane, removing the signal peptides from secretory proteins)
  • HOMOLOGY
    interspecies homolog to yeast imp2
    ortholog to murine Immp2l
    ortholog to chicken immp2l
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • acting as a serine-type peptidase
  • involved in folliculogenesis or male fertility
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) GTS7
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    dysruption of the gene in 1 case of Gilles de la Tourette syndrome
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS