Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | NTS | contributors: mct/npt - updated : 05-02-2010 |
HGNC name | neurotensin |
HGNC id | 8038 |
|
DNA |
TYPE | functioning gene |
STRUCTURE | 8.70 kb 4 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | N | status | confirmed |
Map | cen - D12S1708 - D12S1981 - D12S1670 - D12S319 - D12S1667 - D12S1118 - D12S1214E - D12S323 - D12S33 - D12S855 - D12S1444 - NTS - D12S81 - D12S88 - D12S365 - D12S2039 - D12S1719 - D12S1593 - KITLG - D12S1453 - (D12S2009 ,D12S1250E ) - D12S1429 - (D12S1400 ,D12S1152E ) - ATP2B1 - D12S1122 - D12S5316 - D12S82 - qter |
Authors | Marondel (96),4st Workshop chrom.12 (97) |
RNA |
TRANSCRIPTS | type | messenger |
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|
EXPRESSION |
Type | restricted |
cell lineage
cell lines
| fluid/secretion
| secreted | |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
isoforms | Precursor | neurotensin and neuromedin N are located in the C-terminal region of the precursor (pro-NT/NN) where they are flanked and separated by three Lys -Arg sequences (Kitabgi 2009) |
HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | regulatory , signaling neurotransmitter |
SUBCELLULAR LOCALIZATION | extracellular |
intracellular | |
intracellular,cytoplasm,cytosolic,granule |
basic FUNCTION | |
| |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | nervous system |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
Other | regulation of NTS expression by NR2F2, which may have important consequences for lipid metabolism |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
|
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |