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FLASH GENE
Symbol LUC7L contributors: - updated : 16-12-2005
HGNC name LUC7-like (S. cerevisiae)
HGNC id 6723
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster, opposite orientation
text opposite orientation of alpha globin cluster
STRUCTURE 40.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
motif repetitive sequence   ALU
MAPPING cloned Y linked N status provisional
regionally located at the centromeric boundary of the alpha globin cluster
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 1450 43.7 371 - Tufarelli-Utsch
- splicing 2500 35.8 325 - Tufarelli-Utsch
- splicing 3500 - - - Tufarelli-Utsch
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   moderately
Lymphoid/Immunespleen   highly
 thymus   highly
Nervousbrain   moderately
Reproductivemale systemprostate  moderately
Respiratorylung   moderately
Urinarykidney   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an N terminal conserved region
  • a C3H zinc finger
  • a coiled-coil domain
  • a C2H2 RNA-binding zinc finger motifs
  • two overlapping bipartite nuclear localization signals (NLS)
  • a C-terminal RS/RE (arginine-serine-rich and arginine-glutamate-rich) motif
  • HOMOLOGY
    interspecies ortholog to murine Luc7l
    homolog to rattus Rn.22920
    homolog to zebrafish Dr.4159
    homolog to Drosophila CG7564
    homolog to C.elegans B0495.8a
    homolog to yeast S.cerevisiae luc7
    homolog to xenopus Xl.5806
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    text sarcoplasmic reticulum
    basic FUNCTION unknown
    CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS