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FLASH GENE
Symbol OVGP1 contributors: mct - updated : 03-09-2007
HGNC name oviductal glycoprotein 1, 120kDa (mucin 9, oviductin)
HGNC id 8524
DNA
TYPE functioning gene
STRUCTURE 13.00 kb     11 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
regulatory sequence Promoter
Binding site   HRE
text structure eight half estrogen -responsive element (ERE) and an imperfect ERE site
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland    
Endocrineparathyroid   highly
Nervousbrain    
Reproductivefemale systemoviduct   
 female systemuterus  highly
 male systemprostate   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelial    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
Homologene
FAMILY chitinase protein family
CATEGORY secretory
SUBCELLULAR LOCALIZATION extracellular
    intracellular
intracellular,cytoplasm,cytosolic,granule
text secretory granules
basic FUNCTION
  • playing a role in the fertilization process (sperm capacitation ,sperm-zona binding and zona penetration)and/or early embryonic development
  • binds to both gametes (oocytes and spermatocytes)through its interaction with MYH9 through the non-glycosylated N-terminal conserved region of OVGP1, spanning the residues 11-137
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS