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FLASH GENE
Symbol GALE contributors: mct/npt - updated : 15-05-2013
HGNC name UDP-galactose-4-epimerase
HGNC id 4116
DNA
TYPE functioning gene
STRUCTURE 3.97 kb     11 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
text all transcripts encode the same protein
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
12 - 1647 - 348 - Daude (1995)
12 - 1585 - 348 - Daude (1995)
11 - 1626 - 348 - Daude (1995)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon highly
Reproductivefemale systemuteruscervix highly
Skin/Tegumentskin   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to Drosophila cg-12030
Homologene
FAMILY
  • NAD dependent epimerase
  • sugar epimerase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • bifunctional enzyme catalysing epimerization of UDP glucose and of UDP-N acetylglucosamine
  • catalyses the interconversion of UDP-glucose and UDP-galactose (Timson 2005)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
  • NAD
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) GALED
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS