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FLASH GENE
Symbol GNG13 contributors: KTN/npt - updated : 05/11/2008
HGNC name guanine nucleotide binding protein (G protein), gamma 13
HGNC id 14131
DNA
TYPE functioning gene
STRUCTURE 2.69 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 1001 7.8 67 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Visualeye   specific
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • GGL domain
  • G proton gamma subunit like motifs
  • conjugated LipoP
    mono polymer heteromer , trimer
    HOMOLOGY
    interspecies homolog to chimpanzee GNG13 (100 pc)
    Homologene
    FAMILY
  • G protein gamma family
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    text
  • lipid-anchor
  • cytoplasmic side
  • basic FUNCTION
  • involved as a modulator or transducer in various transmembrane signaling systems
  • required for the GTPase activity with beta chain, for replacement of GDP by GTP, and for G protein-effector interaction
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction , sensory transduction/taste
    a component
  • composed of 3 units, alpha, beta and gamma
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting specifically with the third PDZ domain of DLG4
  • interacting specifically with the sole PDZ domain of LIN7B
  • interacting specifically with the third PDZ domain of DLG1
  • cell & other
    REGULATION
    Other prenylation
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS