basic FUNCTION
| involved in bone formation and remodeling |
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stimulating saturable transport of pyrophosphate ions across the plasma membrane, with half maximal rates attained at physiological levels of pyrophosphate |
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multipass transmembrane protein that is expressed in joints and other tissues |
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regulating intra- and extracellular levels of inorganic pyrophosphate (PPI), probably functioning as PPI transporter |
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plays a central role in bone mineralization, and contributes to the genetic regulation of osteoprotegerin levels |
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pyrophosphate transporter, which regulates tissue calcification |
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regulates inorganic pyrophosphate (PPi) transport |
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may regulate tissue mineralization by transporting pyrophosphate to the extracellular space |
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