Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | AASS | contributors: - updated : 05-05-2006 |
HGNC name | aminoadipate-semialdehyde synthase |
HGNC id | 17366 |
|
DNA |
TYPE | functioning gene |
STRUCTURE | 57.00 kb 23 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
Map | cen - D7S655 - AASS AASS - D7S686 - qter |
Authors | Gene Map (98) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
mono polymer | homomer , dimer |
HOMOLOGY |
interspecies | ortholog to yeast S.cerevisiae LYS1/LYS9 |
ortholog to murine Aass |
Homologene |
FAMILY | |
|
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria |
basic FUNCTION | . bifunctional enzyme catalyzing the first two steps in the mammalian lysine degradation pathway |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | electron transport |
PATHWAY |
metabolism | aminoacid |
signaling |
lysine catabolism |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
induced by | starvation |
ASSOCIATED DISORDERS |
corresponding disease(s) | AASS , SCDD |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |