protein
| CED-1 and CD91/low density lipoprotein receptor-related protein,LRP |
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role for GULP1 as a positive regulator of ARF6 |
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SCARB1 binds to engulfment adapter protein (GULP1) using the C-terminal intracellular domain, and PS-recognizing SCARB1 activates associated GULP1 |
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is able to specifically interact with the NPxF/Y motif of STAB1 cytoplasmic region |
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GULP1-APP interaction is mediated by the NPTY motif of APP and the GULP1 PTB (phosphotyrosine-binding) domain |
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is an adapter to LRP1 and mediates TGFB1 signaling in signaling-competent early endosomes |
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GULP1 mediates LRP1 transactivation |
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PEAR1 associates with GULP1, the mammalian homologue of Ced-6, an adaptor protein required for phagocytosis mediated by the nematode engulfment receptor Ced-1 |
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GULP1 mediates trogocytosis bi-directionally by dynamic engagement with EphB/ephrinB protein clusters in cooperation with the Rac-specific guanine nucleotide exchange factor TIAM2 |