basic FUNCTION
| is thought to have a role in cell survival in neural progenitor cells and to suppress autophagy, a process that needs to be tightly controlled in breast cells during normal development, tissue differentiation, and response to stress |
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plays a critical role in the induction of starvation-induced autophagy as a specific member of PIK3C3 Complex I |
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modulates autophagy via regulation of PI3K-III and prevents ER stress-mediated cytotoxicity and liver injury |
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is potentially involved in autophagosome biogenesis |
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likely expression of NRFB2 might play a role in transformation or progression of transformed breast cells |