basic FUNCTION
| involved in the assembly of adherens junction |
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plays a unique role in the intestine and assign a novel role of this protein in controlling intestinal inflammation by a selective induction of T cell apoptosis and cell cycle restriction |
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tandem-repeat-type galectin that is expressed in the epithelium of the alimentary tract from the tongue to the large intestine |
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involved in epithelial glycoprotein transport |
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is required for axon growth and for the organization of axonal membrane L1 delivery and clustering |
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plays an important role in metastatic process of lung adenocarcinoma |
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role of LGALS4 and other galectins in basolateral to apical epithelial transcytosis |
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may function as a tumor suppressor gene in urothelial carcinoma (UC) progression, and methylation-mediated LGALS4 gene repression may be involved in urothelial tumor progression |
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neurons establish axon membrane domains expressing LGALS4, the first inhibitor of myelination identified in axons, whose regulated boundaries delineate myelination-incompetent axon segments along development |
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may likely exert the immunoregulatory functions through the activation and differentiation of monocytes |
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played a critical role in the progression of urothelial carcinoma of the bladder |