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FLASH GENE
Symbol TP53TG3 contributors: mct/npt - updated : 16/12/2008
HGNC name TP53 target 3
HGNC id 30759
Location 16p11.2      Physical location : 32.684.848 - 33.264.719
Synonym name
  • hypothetical protein LOC24150
  • p53 target gene 3
    • Synonym symbol(s) TP53TG3A, P53TG3
    DNA
    TYPE functioning gene
    STRUCTURE 3.21 kb     2 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 2034 12.7 124 expressed predominantly in testis Ng (1999)
    - - 1879 - 132 expressed predominantly in testis Ng (1999)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrinethyroid   highly
    Reproductivefemale systemplacenta  moderately
     male systemtestis  highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  moderately
    Connectivebone  moderately
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY signaling
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • may play a significant role in p53/TP53-mediating signaling pathway
  • may be playing an important role in the TP53-mediated signaling pathway, when it forms complexes with other protein(s) and is transferred by them into the nucleus
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    p53/TP53-mediating signaling pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by TP53
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS